???? ???? ??? ????? ??? ??? ? ?? ??? ??? ?? ??? ?????.????? ?? ?? ??? ???? ? ????? ???? ?? ???, ?? ?? ??? ????.?? ? ??? ?? ??? ??? ?? ???. ???? ?? ? ????? ?? ??? ????.?? ????? ?????? ?? ??? ??? ???? ????? ?? ?????. ??? ??? ??? ??? ?? ???? ????.????? ?? ?????? ??? ?? ??? ??? ??? ??? ??? ? ????. ??? ??? ???? ?? ??? ???? ???.???? ?? ?? ? ?? ??? ??? ?

Il trattamento con un inibitore della fosfodiesterasi di tipo 5 aumenta la quantità e la permanenza del NO in loco e quindi prolunga e accentua questo rilassamento.Tadalafil had no considerable impact on the pharmacokinetics of theophylline.When tadalafil was administered to topics taking theophylline, a small augmentation (3 beats for each minute